Kibuuka was a Muganda of the Spiny Anti-eaters (Lugave) Clan. He and his friend Achilles Kiwanuka were cousins. His father was Kisuule, an official King’s drummer of Mujaguzo.

His father had many wives and about thirteen children almost all girls. Kibuuka was almost the only boy that is why he was also called Katekamulungaggana, in short Katekamu – the only boy among many girls.

Kibuuka with his cousin Kiwanuka and another boy Kigongo Ssemmindi Luinga were taken to King Mwanga’s palace and served as pages. By then he was sixteen years of age and were all put under the care of Charles Lwanga who converted all the three boys to Catholicism.

Kibuuka was active social, talented and active in games, music and always cheerful, and charitable. He was a boy and hardly showed tiredness. On taking up Christianity, Kibuuka abandoned all his witchcraft and burnt it. He begged for baptism and he was baptised on Monday night 16^th November, 1885.

When the Christian persecution broke out, Ambrose and his cousin Achilles were arrested. Their friend Kigongo went back and informed the parents of his friend’s arrest, they were arrested on Wednesday morning 26^th May 1886 and were both in the group of Charles Lwanga. They were taken to Namugongo, and burnt to death on Thursday noon, 3^rd June, 1886 at the age of 18.

Ambrose is the patron of socialists and youth movements such as scouts and Xaverians.